Archive for the ‘Science’ Category

Hey you! Yes you! Do you like mimes? What about singing steampunk mime robots? I sure do! As esoteric as that may sound there is a band for that, Steam Powered Giraffe. It may sound a little kitchy and weird but they are like nothing else you have heard.

They also have a new album coming out right before my birthday in a couple weeks, I can’t wait. I just need them to come up to the Bay Area on tour now.

See an updated version of this post on The Leaf Online,Cannabinoid Profile – CBG!

Cannabigerol
Formula: C21H32O2
Molecular Mass: 314.2246 g/mol
Decaboxylation Point: ????
Boiling Point:  ????
LD50 (Lethal Dose): 300mg/kg for mice (Compare to Nicotine: for mice – 3mg/kg for humans – 40–60 mg/kg)

Cannabigerol (CBG) is not considered psychoactive  and is known to block the psychoactive effects of THC.  It has been shown to stimulate the growth of new brain cells and bones. Neurogenic compounds are extremely rare which makes CBG a very worthwhile subject for more research. CBG also is antibacterial, anti-tumor, and aids with insomnia. It is effectively impossible to overdose on CBG; it usually exists only in trace amounts in a processed plant, this makes the already very high LD50 of 22.44g/kg even less. CBG is considered a ‘stem cell’ cannabinoid and can change into different cannabinoids, altering the overall effects of the plant. Some of these cannabinoids CBG morphs into are  THC ,CBD, and CBC which all share the same molecular formula but have a different structure.

Therapeutic Uses

Analgesic – Relieves pain.

Antibacterial – Slows bacterial growth.
Anti-Inflammatory – Reduces inflammation systemically.
Anti-Insomnia – Aids with sleep.
Anti-Proliferative – Inhibits cancer cell growth.
Bone Stimulant – Promotes bone growth.
Neurogenic – Helps stimulate the growth of new brain cells.

Currently Being Studied For

Glaucoma: A 2009 study found both CBG and THC to be very effective for relieving the intraocular pressure from glaucoma. This is an area that will undoubtedly be receiving more research in the years to come.

Inflammatory Bowel Disease: Much like CBD, CBG shows a lot of potential for controlling the inflammation that leads to IBD, and like CBD warrants further research.

Painkiller and Anti- Inflammatory: Recent research suggests that CBG has anti-inflammatory and analgesic properties and recommends further study.

5-HT1a Receptor Agonist/Antagonist?: CBG appears to do something at the 5-HT1a receptor that is not fully understood. It modulates how other cannabinoids affect us especially at this brain site, which is the hub of emotions and depression regulation in the brain. Depending on the study evidence suggests that CBG may help your depression and anxiety, or possibly block certain anti-depressant drugs. One study in rodents showed that if the right combination of CBG and CBD were present the CBG would block some of the anti-nausea effects of the CBD, but it could not quite identify why (other than it related to the 5HT1a receptor).

Dravet Syndrome/Seizures: Anecdotal evidence and some current studies suggest that CBG may be beneficial to patients with Dravet and other seizure conditions. A new tincture was just released at Harborside Health Center which is the first CBG-rich tincture on the market. This tincture, named Jayden’s Juice after Jayden David, the young boy with Dravet syndrome made famous by Weed Wars, is currently what Jayden is using to combat his seizures instead of a purely CBD rich tincture. A study from earlier this year also suggests that CBG may help with seizure management, but the mechanisms aren’t fully understood.

Halent 2011 - Cannabinoid and Terpenoid Chart

References:

  1. Steep Hill Lab, Cannabinoid and Terpenoid Reference Guide; http://steephilllab.com/resources/cannabinoid-and-terpenoid-reference-guide/
  2. Skunk Pharm Research, Cannabinoid and Terpene Info; http://skunkpharmresearch.com/cannabinoid-info/
  3. SC Labs, Meet the Cannabinoids; http://sclabs.com/learn/learn-cannabinoids.html

*Note: Decarboyxlation – A chemical reaction that removes a carboxyl group and releases  CO2, often triggered by heat.

I was just linked to an amazing new invention and it’s corresponding kickstarter campaign. The Fly Kly Smart Wheel turns any back wheel into an electric motor that can crank you up 20 extra mph. I have long wanted to take my awesome folding Montague X50 and make it into a space-age folding bicycle that I can take inside buses and trains. People already ask me if it is electric, I really wish it was. I love the work out of cycling, I rely on it in my weekly routine, but since I usually ride in suits some assistance would be nice on my way to work to not mess my suit up. My worry is that it looks like it may be for single speed bikes only. I don’t know if I can fit my gears around the motor, but I want to try!

Unfortunately, the $800 security deposit I was getting refunded, which could have donated to their campaign and got me a Fly Kly Smart Wheel, is instead going to pay for numerous medical bills due to my crash. Awesome. I may still find a way, there are 25 days left in there campaign and I can always buy one later.

For my first post permit me to humor my love of the movie Dune.

A Beginning Is A Very Delicate Time. Know then that my name is Mitchell Colbert and it is the year 2013. The Known Universe is ruled by a panoptic technology that is enmeshed in everything we do, called The Internet. In this time, cool kids write about what they do and post it on the Internet for complete strangers to read it, and maybe laugh, and perhaps expand their consciousness. The Internet is vital to modern life and available even during space travel.
Humanity, and a subspecies of Trolls who have been mutated by thousands of hours on /b/, use the Internet to read the news, watch funny cat videos, and post 140 character updates to Twitter. We can stay connected to any part of the universe without moving from our chairs.

I’m done paraphrasing Dune for now, but I felt it an appropriate way to start things off. Now that I have gotten the ball rolling permit me to tell you why I have decided to create this blog and join the ranks of those illustrious cool kids who tell people about what they do on the Internet.

This blog is not a political blog, it is not a photography blog, cooking blog, DIY blog, or any sort of themed blog, but it will probably include all those topics and more. This blog is about things that stir up my passions so much that I need to share them with the world. Expect political posts to keep you up to date on the news the networks don’t cover, expect me to share life hacks to make your life easy mode, and expect me to post plenty of recipes/photos/poems. I am a person who views knowledge as a communal good that should be shared with as many people as possible, this blog is my means to that end.

I will be trying to post with some regularity, once or twice a week. That may not always happen since, unlike professional bloggers, I don’t get paid to write this and work a real job, at the world’s largest medical cannabis dispensary, Harborside Health Center. You may now be wondering how much of a real job working at a medical cannabis collective actually is, read on, dear readers, and find out.

A beginning truly is a very delicate time, and how something begins can predict how well it will fair. I picked today